An oral challenge with the offending food or drug may be required after completing your skin testing. During the oral challenge, increasing amounts of the food or drug will be given to see if you are still allergic. This testing may take several hours.

More serious reactions to skin testing or oral challenges to foods or drugs may include:
Systematic reactions may also occur, but are uncommon. These reactions include itchy eyes, nose or throat; nasal congestion; runny nose; sneezing; tightness in the throat or chest; increased wheezing; lightheadedness; faintness; nausea and vomiting; hives; generalized itching; and shock that could be potentially fatal/ Please notify the medical staff or physician if you have any of these symptoms. If you were to have any of these symptoms, you may be treated with epinephrine (adrenaline), antihistamines, intravenous fluids, or steroids.