Subcutaneous immunoglobulin (SCIG)

Immunoglobulins are antibodies made by our immune system that help fight infections.  Patients with immune deficiencies may lack antibodies (immunoglobulins) or the antibodies may not work properly.   These replacement immunoglobulins are collected from thousands of healthy blood donors and consist of sterile solutions of concentrated antibody.  The solutions of immunoglobulins are related to decrease the transmission of known pathogens.

Infusion of immunoglobulins can be given subcutaneously.  SCIG can be given weekly to monthly.

There are several advantages to SCIG over intravenous immunoglobulin (IVIG).  SCIG can be given at home and a patient can do it themselves.   Side effects are typically less with SCIG compared to IVIG.   The levels don’t fluctuate as much with SCIG.